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Estrogen allergy testing mayo clinic buy genuine prednisone, progesterone, and other hormones stimulate the growth of the breasts during pregnancy. Sex-linked traits Sex-linked traits are traits affected by genes on the sex chromosomes. X-linked traits are affected by genes on the X chromosome, and Y-linked traits are affected by genes on the Y chromosome. X-linked traits are seen more frequently in males than in females because males have only one X chromosome. A carrier for a recessive trait is heterozygous for the trait, having one normal allele and one disorder-causing allele. Some genetic disorders result from an abnormal distribution of chromosomes during gamete formation. A Punnett square can determine the probability of particular alleles being transmitted to the next generation. Given these structures: (1) mesonephros (2) metanephros (3) pronephros Choose the arrangement that lists the structures in the order in which they form during development. Choose the arrangement that lists the structures in the order in which they form during development. A study of the early embryo indicates that the glans penis of the male develops from the same embryonic structure as which of these female structures Which hormones cause the differentiation of sex organs in the developing male fetus Approximately how many days has the embryo been developing, and what developmental events are occurring Three minutes after birth, a newborn has an Apgar score of 5 as follows: A, 0; P, 1; G, 1; A, 1; and R, 2. When a woman breastfeeds, milk letdown can occur in the breast that is not being suckled. An 18-year-old woman consulted a physician because of her failure to initiate menses. She had experienced normal breast development at age 13, but no pubic or axillary hair had ever appeared. Her height was 5 feet 6 inches, weight 119 pounds, blood pressure 110/70, and pulse 60 beats/minute. Her physical examination confirmed the presence of well-developed breasts and the external genitalia of a normal female. However, the vagina ended in a blind pouch, and there was no evidence of a cervix, ovaries, or a uterus. Within the inguinal area, the examining physician could palpate a small, spherical mass on each side. The modern periodic table of the elements lists the known elements in order of their atomic masses.

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Neurons in the medullary respiratory center establish the basic rhythm of ventilation allergy testing uk food prednisone 20 mg purchase on line. When stimuli from receptors or other parts of the brain exceed a threshold level, inspiration begins. As respiratory muscles are stimulated, neurons that stop inspiration are stimulated. When the stimulation of these neurons exceeds a threshold level, inspiration is inhibited. Cerebral and Limbic System Control Ventilation can be voluntarily controlled and can be modified by emotions. Oxygen levels in the blood affect ventilation when a 50% or greater decrease from normal exists. Decreased O2 is detected by receptors in the carotid and aortic bodies, which then stimulate the respiratory center. Hering-Breuer Reflex Stretch of the lungs during inspiration can inhibit the respiratory center and contribute to a cessation of inspiration. Collateral fibers from motor neurons and from proprioceptors stimulate the respiratory centers. Chemosensitive mechanisms and learning fine-tune the effects produced through the motor neurons and proprioceptors. Other Modifications of Ventilation Touch, thermal, and pain sensations can modify ventilation. Vital capacity and maximum minute volume decrease with age because of weakened respiratory muscles and decreased thoracic cage compliance. Residual volume and dead space increase because of the enlarged diameter of respiratory passageways. An increase in resting tidal volume compensates for decreased alveolar ventilation, loss of alveolar walls (surface area), and thickening of alveolar walls. During an asthma attack, a person has difficulty breathing because of constriction of the a. A smaller pressure gradient is required to get the same rate of airflow, compared with normal bronchioles. Immediately after the creation of an opening through the thorax into the pleural cavity, a. Given these lung volumes: (1) tidal volume = 500 mL (2) residual volume = 1000 mL (3) inspiratory reserve volume = 2500 mL (4) expiratory reserve volume = 1000 mL (5) dead space = 1000 mL the vital capacity is a.

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The olfactory epithelium allergy symptoms child purchase prednisone 5 mg with mastercard, the sensory organ for smell, is located in the most superior part of the nasal cavity (see figure 15. For example, most people know immediately when you have a cold because your voice sounds different. Conducting Zone the conducting zone structures are well adapted for the movement, cleaning, warming, and humidification of air. Air is simply moved from the external environment to areas deep inside the lungs, which are in contact with blood capillaries. Nose the nose, or nasus (nss), consists of the external nose and the nasal cavity. The external nose is the visible structure that forms a prominent feature of the face. The largest part of the external nose is composed of hyaline cartilage plates (see figure 7. The nasal bones plus extensions of the frontal and maxillary bones constitute the bridge of the nose, which is where eyeglasses would rest. The nasal cavity is the open chamber inside the nose where air first enters the respiratory system. Just inside each naris, in the anterior part of the nasal cavity, is the region called the vestibule (vesti-bool; entry room). The vestibule is lined with stratified squamous epithelium, which is continuous with the stratified squamous epithelium of the skin. The choanae in the posterior part of the nasal cavity are the openings into the pharynx. It is covered by a highly vascular mucous membrane that forms the floor of the nasal cavity. The nasal cavity is divided into right and left halves by a partition called the nasal septum. The anterior part of the nasal septum is composed of cartilage, while the posterior part consists of the vomer bone and the perpendicular plate of the ethmoid bone. There are three lateral bony ridges called conchae (konk; resembling a conch shell) on each side of the nasal cavity. The conchae used to be named the turbinate bones because they act as "wind turbines," helping the air churn through the nasal cavity. Within the superior and middle meatuses are openings from the various paranasal sinuses (see figure 7. Each inferior meatus also contains the opening of a nasolacrimal (n-z-lakri-ml) duct for tear drainage from the surface of the eye (see figure 15. Pharynx the pharynx (faringks; throat) is the common opening of both the digestive and the respiratory systems. It receives air from the nasal cavity and receives air, food, and drink from the oral cavity. Viral infections, such as the common cold, can cause mucous membranes to become inflamed and swollen and to produce excess mucus.

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Some societies consider blood the "essence of life" because the uncontrolled loss of it can result in death allergy testing des moines 20 mg prednisone overnight delivery. For example, people from prominent families are sometimes described as "bluebloods," whereas criminals are said to have "bad blood. Blood performs many functions essential to life and can often reveal much about our health. Blood is one component of the cardiovascular system, which also consists of the heart and the blood vessels. The heart pumps blood through vessels extending throughout the body (often referred to as the circulatory system), and the blood delivers nutrients and picks up waste products at the body tissues. This chapter focuses on the blood, whereas chapters 20 and 21 discuss the heart and the blood vessels, respectively. Carbon dioxide, produced by the cells, is carried in the blood to the lungs, where it is exhaled. Many substances are produced in one part of the body and transported in the blood to another part, where they are modified. For example, the precursor to vitamin D is produced in the skin (see chapter 5) and transported by the blood to the liver and then to the kidneys for processing into active vitamin D. The blood then transports active vitamin D to the small intestine, where it promotes the uptake of calcium. Another example involves lactate produced by skeletal muscles during anaerobic respiration (see chapter 9). The blood carries the hormones and many of the enzymes that regulate body processes from one part of the body to another. The osmotic composition of blood is also critical for maintaining normal fluid and ion balance. Body temperature regulation involves several mechanisms, including the movement of warm blood from the interior of the body to its surface, where heat is released. Certain cells and chemicals in the blood make up an important part of the immune system, protecting against foreign substances, such as microorganisms and toxins. Blood clotting protects against excessive blood loss when blood vessels are damaged. The blood clot that forms in damaged tissue is also the first step in tissue repair and the restoration of normal function (see chapter 4). Blood is a type of connective tissue consisting of a liquid matrix containing cells and cell fragments. Plasma is the liquid matrix, and the formed elements are the cells and cell fragments. The plasma makes up 55% of the total blood volume, and the formed elements make up 45% (figure 19. It is a pale yellow fluid that consists of about 91% water and 9% other substances, such as proteins, ions, nutrients, gases, waste products, and regulatory substances (table 19.

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An upper esophageal sphincter and a lower esophageal sphincter allergy treatment with honey generic prednisone 40 mg, at the upper and lower ends of the esophagus, respectively, regulate the movement of materials into and out of the esophagus. Numerous mucous glands in the submucosal layer produce a thick, lubricating mucus, which passes through ducts to the surface of the esophageal mucosa. Swallowing Phases Swallowing, or deglutition, is divided into three phases: voluntary, pharyngeal, and esophageal. This phase of swallowing begins with the elevation of the soft palate, which closes the passage between the nasopharynx and oropharynx. The pharynx elevates to receive the bolus of food from the mouth and moves the bolus down the pharynx into the esophagus. The superior, middle, and inferior pharyngeal constrictor muscles contract in succession, forcing the food through the pharynx. At the same time, the upper esophageal sphincter relaxes, the elevated pharynx opens the esophagus, and food is pushed into the esophagus. This phase of swallowing is unconscious and is controlled automatically, even though the muscles involved are skeletal. The pharynx and larynx are elevated (blue arrows indicate muscle movement; green arrow indicates elevation of the larynx). As this occurs, the vestibular and vocal folds expand medially to close the passage of the larynx. The epiglottis (green arrow) is bent down over the opening of the larynx largely by the force of the bolus pressing against it. Opening of larynx Inferior pharyngeal constrictor Upper esophageal sphincter Esophagus 4 Esophagus 5 4 As the inferior pharyngeal constrictor contracts, the upper esophageal sphincter relaxes (outwardly directed blue arrows), allowing the bolus to enter the esophagus. Predict 3 Why is it important to close the opening between the nasopharynx and the oropharynx during swallowing What may happen if a person emits an explosive burst of laughter while trying to swallow a liquid Its shape and size vary from person to person, even within the same individual from time to time, depending on food content and body posture. Anatomy of the Stomach the opening from the esophagus into the stomach is the gastro-esophageal opening, or cardiac (located near the heart) opening, and the region of the stomach around the cardiac opening is the cardiac part (figure 24. The lower esophageal sphincter, also called the cardiac sphincter, surrounds the cardiac opening. Recall that, although this is an important structure in the normal function of the stomach, it is a physiological constrictor only and cannot be seen anatomically. The part of the stomach to the left of the cardiac part, the fundus (fnds), is actually superior to the cardiac opening.

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In addition allergy forecast georgetown purchase prednisone with amex, blood levels of other nutrients, neural stimulation, and hormones control the secretion of insulin. Hyperglycemia, or elevated blood levels of glucose, directly stimulates insulin secretion from cells. In addition, the sympathetic nervous system can directly reduce insulin secretion. Conversely, certain amino acids stimulate insulin secretion by acting directly on the cells. Thus, after a meal, when glucose and amino acid levels in the blood are their highest, insulin secretion increases. During periods of fasting, when blood glucose levels are low, the rate of insulin secretion declines (figure 18. Parasympathetic stimulation associated with food intake acts with the elevated blood glucose levels to increase insulin secretion. Sympathetic innervation inhibits insulin secretion and helps prevent a rapid fall in blood glucose levels. Because most tissues, except nervous tissue, require insulin to take up glucose, sympathetic stimulation maintains blood glucose levels in a normal range during periods of physical activity or excitement. Gastrointestinal hormones involved with regulating digestion, such as gastrin, secretin, and cholecystokinin (see chapter 24), increase insulin secretion. Somatostatin inhibits insulin and glucagon secretion, but the factors that regulate somatostatin secretion are not clear. It can be released in response to food intake, in which case somatostatin may prevent the oversecretion of insulin. Describe the nervous and hormonal interactions during exercise that will provide enough energy to cells. The interactions of these hormones is illustrated in two situations-after a meal and during exercise. Both increasing blood glucose levels and parasympathetic stimulation elevate insulin secretion to increase the uptake of glucose, amino acids, and lipids by target 3 Stimulus Receptors and control centers: Pancreas: Pancreatic islets detect an increase in blood glucose and secrete insulin. Intestine: Digestive hormones (gastrin, secretin, cholecystokinin) stimulate insulin secretion. Autonomic Nervous System: Parasympathetic stimulation of pancreas promotes insulin secretion. Stimulus Receptors and control centers: Pancreas: Pancreatic islets detect a decrease in blood glucose and do not secrete insulin. Autonomic Nervous System: Sympathetic stimulation of the pancreas inhibits insulin secretion, including during exercise. Response Effectors: Decreased insulin results in decreased glucose uptake, increased glycogen breakdown by the liver and skeletal muscle, and increased glucose synthesis in the liver.

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When discussing the human life span from a biological perspective allergy testing portland buy prednisone 20 mg without prescription, we subdivide it in multiple ways. From the broadest perspective, we divide the human life span into two major periods: prenatal (before birth) and postnatal (after birth). The prenatal period, which extends from conception until birth, is subdivided into three stages: 1. The germinal period begins at fertilization and ends at 14 days (weeks 1 and 2 of development). The fetal period extends from 56 days after fertilization to birth (the last 30 weeks of development). During this stage, the organ systems grow and become more mature, and the developing human is called a fetus (ftus). The above description characterizes each period based on days from fertilization, or the postovulatory age. Essentially, the foundation of the human body is established early in this period and the first important steps of growth Fertilization Prenatal development begins at fertilization. Fertilization occurs when a sperm cell attaches to a secondary oocyte, and the contents of the sperm head enter the oocyte cytoplasm and join with the oocyte pronucleus (figure 29. Of the several hundred million sperm cells deposited in the vagina during sexual intercourse, only a few dozen reach the vicinity of the secondary oocyte in the ampulla of the uterine tube. The corona radiata, composed of cumulus cells expelled from the follicle with the oocyte during ovulation (see figure 28. The flagella on the sperm cells propel them through the loose matrix between the follicular cells of the corona radiata. Between the corona radiata and the oocyte is the zona pellucida, an extracellular membrane comprised mostly of glycoproteins. This binding initiates the acrosomal reaction, which activates digestive enzymes in the acrosome, primarily hyaluronidase. When the second meiosis is complete, the oocyte nucleus, now called the female pronucleus, moves back toward the center of the oocyte. Changes in the zona pellucida (moving away from the oocyte) form a perivitelline space and prevent additional sperm cells from entering the oocyte. This in turn causes the oocyte to release water and other molecules from secretory vesicles, referred to as cortical granules. The released fluid causes the oocyte to shrink and the zona pellucida to denature and expand away from the oocyte. This results in a fluid-filled space between the oocyte plasma membrane and the zona pellucida called the perivitelline space.

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Replacement therapy allergy symptoms due to weather effective 5 mg prednisone, which includes transfusions of whole blood, plasma, artificial solutions called plasma substitutes, and physiological saline solutions, is administered to increase blood volume. Patients in anaphylactic (anf-laktik; allergic) shock are given anti-inflammatory substances, such as glucocorticoids and antihistamines. The basic objective in treating shock is to reverse the condition and prevent it from progressing to the irreversible stage, as well as to reestablish normal blood flow through tissues. Several types of shock can be classified by cause: Hemorrhagic shock is caused by external or internal bleeding that reduces blood volume. Plasma loss shock is reduced blood volume due to loss of plasma into the interstitial spaces and greatly increased blood viscosity. Causes of plasma loss shock include intestinal obstruction, in which a large amount of plasma moves from the blood into the intestines, and severe burns, which cause large amounts of plasma to be lost from the burned surface. Neurogenic shock is a rapid loss of vasomotor tone, leading to vasodilation so extensive that blood pressure declines severely. Anesthesia includes deep general anesthesia and spinal anesthesia that decrease the activity of the medullary vasomotor center or the sympathetic nerve fibers. Emotional shock (vasovagal syncope) stems from emotions that cause strong parasympathetic stimulation of the heart and results in vasodilation in skeletal muscles and in the viscera. Anaphylactic shock results from an allergic response in which the release of inflammatory substances increases vasodilation and capillary permeability. Septic shock results from peritoneal, systemic, and gangrenous infections that cause the release of toxic substances into the blood (blood poisoning), depressing the activity of the heart and leading to vasodilation and increased capillary permeability. Cardiogenic shock occurs when the heart stops pumping in response to various conditions, such as heart attack or electrocution. As blood pressure increases, some fluid is forced from the capillaries into the interstitial spaces. As blood pressure falls, interstitial fluid moves into capillaries, and this fluid movement resists a further decline in blood pressure. Fluid shift is a powerful mechanism by which blood pressure is maintained, because the interstitial volume acts as a reservoir and is in equilibrium with the large volume of intercellular fluid. The fluid shift mechanism begins to act within a few minutes of a stimulus, but it requires hours to achieve its full functional capacity. It plays a very important role when dehydration develops over several hours, or when a large volume of saline is administered over several hours. Conversely, when blood volume increases rapidly, as occurs during a transfusion, blood pressure increases, and smooth muscle cells of the blood vessel walls relax, resulting in a more gradual increase in blood pressure. The stressrelaxation mechanism is most effective when changes in blood pressure occur over a period of many minutes. Predict 9 Explain the various mechanisms that regulate blood pressure in response to the rapid loss of a large volume of blood, compared with the loss of the same volume of blood over a period of several hours. Stress-Relaxation Response A stress-relaxation response is characteristic of smooth muscle cells (see chapter 9). When blood volume suddenly declines, blood pressure also decreases, reducing the force applied to smooth muscle cells in blood vessel walls.

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Opportunistic infections involve organisms that normally do not cause disease but do so when the immune system is depressed allergy shots video prednisone 20 mg order with visa. Without helper T cells, cytotoxic T- and B-cell activation is impaired, and adaptive resistance is suppressed. Examples of opportunistic infections include pneumocystis (noo-m-sistis) pneumonia (caused by an intracellular fungus, Pneumocystis carinii), tuberculosis (caused by an intracellular bacterium, Mycobacterium tuberculosis), syphilis (caused by a sexually transmitted bacterium, Treponema pallidum), candidiasis (kan-di-d-sis; a yeast infection of the mouth or vagina caused by Candida albicans), and protozoans that cause severe, persistent diarrhea. Kaposi sarcoma is a type of cancer that produces lesions in the skin, lymph nodes, and visceral organs. Even if viral load decreases to the point that the virus is undetected in the blood, the virus still remains in cells throughout the body. Explain how innate, antibody-mediated, and cellmediated immunity can function together to eliminate an antigen. Although the immune system can be described in terms of innate, antibody-mediated, and cell-mediated immunity, these categories are artificial divisions used to emphasize particular aspects of immunity. Actually, there is only one immune system, but its responses often involve components of more than one type of immunity (figure 22. For example, although adaptive immunity can recognize and remember specific antigens, once recognition has occurred the antigen is destroyed with the help of many innate immunity activities, including inflammation and phagocytosis. Describe how interactions among innate, antibodymediated, and cell-mediated immunity can protect the body from an antigen. In this section, we discuss the second benefit, immunotherapy, which treats disease by altering immune system function or by directly attacking harmful cells. For example, administering cytokines or other agents can promote inflammation and activate immune cells, which can help destroy tumor cells. For example, multiple sclerosis is an autoimmune disease in which the immune system treats self-antigens as foreign antigens, thereby destroying the myelin that covers axons. The ability to produce monoclonal antibodies may result in effective treatments for tumors. If an antigen unique to tumor cells can be found, monoclonal antibodies can deliver radioactive isotopes, drugs, toxins, enzymes, or cytokines that kill the tumor cell directly or activate the immune system to kill the cell. Unfortunately, so far researchers have found no antigen on tumor cells that is not also present on normal cells. For example, tumor cells may have more surface antigens of a particular type than normal cells, resulting in greater treatment delivery. Tumor cells may also be more susceptible to damage, or normal cells may be better able to recover from the treatment. One problem with monoclonal antibody delivery systems is that the immune system recognizes the monoclonal antibody as a foreign antigen. After the first exposure, a memory response quickly destroys the monoclonal antibodies, rendering the treatment ineffective. In a process called humanization, the monoclonal antibodies are modified to resemble human antibodies. Some uses of monoclonal antibodies to treat tumors are yielding promising results.

Milten, 53 years: It resembles a walnut in shape and size and is approximately 4 cm long and 2 cm wide. However, if the rate of emptying is too slow, the highly acidic contents of the stomach may damage the stomach wall and reduce the rate at which nutrients are digested and absorbed. The heart generally decreases in size after approximately age 65, especially in people who are not physically active.

Frithjof, 37 years: Hyperventilation activates alveoli not in use because increasing alveolar oxygen and decreasing alveolar carbon dioxide cause lung arterioles to relax, thereby increasing blood flow through the lungs. Percent the weight-volume method of expressing percent concentrations states the weight of a solute in a given volume of solvent. Calcium is actively absorbed by the epithelial cells of the small intestine, and the synthesis of transport proteins in the intestinal cells requires active vitamin D.

Ali, 48 years: Given these arteries: (1) common iliac (3) femoral (2) external iliac (4) popliteal Choose the arrangement that lists the arteries in order, from the aorta to the knee. However, if scientists place intestinal or fecal microbiota from normal mice into the gut of germ-free mice, the immune tissues of the germ-free mice begin developing and functioning normally. Gingivitis (jin-ji-vtis) is an inflammation of the gingiva, often caused by food deposited in gingival crevices and not promptly Salivary Glands A considerable number of salivary glands are scattered throughout the oral cavity.

Peratur, 57 years: Action potentials are conducted by sensory neurons from the genitals through the pudendal nerve to the sacral region of the spinal cord, where reflexes that result in the male sexual act are integrated. Why is it important to maintain blood glucose levels during the postabsorptive state They are actively reabsorbed in the proximal convoluted tubules and actively secreted in the distal convoluted tubules and collecting ducts.

Lars, 50 years: The wall of the proximal convoluted tubule is composed of simple cuboidal epithelium. This may occur in pneumonia or in pulmonary edema resulting from failure of the left ventricle. In October, when the leaves from those trees began to fall, Maddie raked them up and stuffed them into several large garbage bags.

Arakos, 28 years: The female reproductive system nurtures the developing fetus in the uterus until birth and provides nourishment (milk) after birth. The host provides the parasite with the conditions and food necessary for survival. Aging results in gradual changes in heart function, which are minor under resting conditions but more significant during exercise.

Kayor, 41 years: Because of the all-or-none properties of neurons, one action potential has the same magnitude as another. Thus, intra-alveolar pressure rises over barometric air pressure to approximately +1 mm Hg. The presence of food in the esophagus stimulates the myenteric plexus, which controls the peristaltic waves.

Zapotek, 60 years: Reabsorption in the Loop of Henle As the filtrate from the proximal convoluted tubule moves toward the loop of Henle, the wall of the tubule undergoes a histological change. Contraction waves 2 3 Material (brown) in the intestine is spread out in both directions from the site of introduction. The kidneys play a major role in controlling the extracellular fluid volume in the body by producing either a large volume of dilute urine or a small volume of concentrated urine, depending on the hydration level of the body.

Rocko, 34 years: In mild cases of compensated shock, baroreceptor reflexes can compensate for blood loss until blood volume is restored but, in more severe cases, all the mechanisms described are required to compensate for the blood loss. The ability to produce monoclonal antibodies may result in effective treatments for tumors. The distal convoluted tubule also plays a major role in secretion, which is discussed later in this section.

Hector, 61 years: If you have flown on a plane, or have been to the mountains, you may have experienced a situation similar to that which keeps the alveoli expanded. Again, as with the production of concentrated urine, beneficial substances are retained, and both toxic substances and excess water are eliminated. These treatments are followed by the oral administration of the appropriate amount of T3 and T4.

Orknarok, 55 years: Usually, the opening is intended to be permanent, and a tube is inserted into the trachea to allow airflow and provide a way to remove secretions. Stages of Labor Uterine contractions force the fetus out of the uterus during labor. Other fatty acids, such as omega-9 fatty acids, can be synthesized from essential fatty acids.

Tragak, 47 years: Discuss the causes and symptoms of hyposecretion and hypersecretion of adrenal cortex hormones. We can see that the crossover of axons for the fasciculus gracilis tract occurs in the medulla, which is part of the brainstem. Anaerobic Glycolysis Anaerobic (an-r-bik) glycolysis is the breakdown of glucose in the absence of oxygen.

Kulak, 52 years: Chylomicrons enter the lymphatic capillaries rather than the blood capillaries because the lymphatic capillaries lack a basement membrane and are more permeable to large particles, such as chylomicrons, which are about 0. Molecules not immediately needed for energy are stored: Glucose is converted to glycogen or triglycerides, triglycerides are deposited in adipose tissue, and amino acids are converted to triglycerides or carbohydrates. For example, during exercise, increased arterial blood pressure is needed to sustain increased blood flow through the capillaries of skeletal muscles, in which precapillary sphincters have dilated.

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